Clinical study on rectal administration of controlled-release tablet of morphine hydrochloride in the treatment of cancer pain 盐酸吗啡缓释片经直肠给药治疗癌性疼痛的临床研究
Oh, God, for some morphia! Morphine [ Hydrochloride, Sulfate] 啊,上帝,弄点吗啡来吧!
Morphine [ Hydrochloride, Sulfate] Determination of dimethyl sulfate in quaternary ammonium salt surfactant by headspace gas chromatography 吗啡[盐酸盐,硫酸盐]顶空气相色谱法测定季铵盐型表面活性剂中硫酸二甲酯
Results: In the volume of use, the most three are Durogesic patch, Morphine hydrochloride controlled-release tablets, and Pethidine hydrochloride injection. 结果:麻醉药品用量前三位是多瑞吉贴膜、盐酸吗啡控释片、盐酸哌替啶注射液。
RP-HPLC simultaneous determination of morphine, ephedrine hydrochloride and codeine phosphate in Xiaochuan tablets RP-HPLC法同时测定哮喘片中吗啡、盐酸麻黄碱、磷酸可待因的含量
Methods: Mice were administered ( sc) with morphine hydrochloride to establish morphine dependence model. 方法:皮下注射(sc)盐酸吗啡建立吗啡依赖小鼠实验模型,在纳洛酮催促戒断前30min侧脑室微量注射甲氧氯普胺,观察其急性给药对吗啡依赖性戒断症状的影响;
Methods Conditioned place preference ( CPP) was established in Sprague Dawley rats with morphine hydrochloride ( 4mg · kg~-1) training. Brain tissues were dissected out and homogenized. 方法用4mg·kg-1盐酸吗啡对雄性SD大鼠进行条件性位置偏爱(CPP)训练。
Conclusions The morphine hydrochloride sustained-release tablet is a kind of safe and effective analgesic to advanced aged cancer patients with pain. 结论高龄癌痛患者应用美菲康进行镇痛治疗是安全有效的。
Conclusion Morphine hydrochloride sustained-release tablets have a significant therapeutic effect on the cancer pain with lower side effect of toxicity and higher safety. 结论盐酸吗啡缓释片治疗癌症疼痛疗效显著,毒副反应轻,安全可行。
Drugs: CNL extract was provided by the Department of Phytochemistry, Shenyang Pharmaceutical University ( batch number: 2002080901), morphine hydrochloride injection by Shenyang No. 药品:夜来香提取物由沈阳药科大学植化教研室提供(药品批号:2002080901);
Conclusions Morphine hydrochloride sustained release tablets were effective on the treatment of cancer pain, and capable of improving cancer patients ′ life quality. They should be the first selective medicine for the treatment of moderate-severe cancer pain. 结论盐酸吗啡缓释片能有效控制癌性疼痛,提高癌症患者的生活质量,是治疗癌性中重度疼痛的理想药物。
Effects of morphine hydrochloride on mice serum nitric oxide level 吗啡对小鼠血清一氧化氮含量的影响
Morphine physical dependence was induced on day 10 in SD rats by daily administration of morphine sulphate ( MS), but not morphine hydrochloride ( MH), in their drinking water. 在饮水中溶入硫酸吗啡,逐日提高吗啡浓度,SD大鼠在饮入吗啡后第10天产生明显的吗啡依赖。而同样方法饮入盐酸吗啡效果较差。
Conclusion: Morphine sulphate is better than morphine hydrochloride in inducing morphine dependence in rats. 结论:经自饮摄入法诱导吗啡依赖大鼠时,硫酸吗啡的效果优于盐酸吗啡。
Clinical Observation on the Treatment of Cancer Pain by Morphine Hydrochloride Sustained Release Tablets 盐酸吗啡缓释片治疗癌性疼痛的临床观察
Aim: To study the pharmacokinetics in the rabbits of morphine hydrochloride loaded into erythrocyte ( M-RBC). 目的:通过对高渗法制备的吗啡红细胞载体(M-RBC)在兔体内的药代动力学研究,考察M-RBC缓释效应。
Studies on standard for the quality of morphine hydrochloride 盐酸吗啡质量标准增订的分析研究
Tolerance to systemic morphine was induced by morphine hydrochloride ( 10mg/ kg i. h) for 9 consecutive days. 全身吗啡耐受大鼠模型的建立采用连续9天皮下注射吗啡10mg/kg的方法;
With a does of 0.3mg/ kgx7d, 0.6mg/ kgx7d, ip in mice, the morphine hydrochloride could increased obviously the weights of thymus and spleen, and the phagocytic rate and index of peritoneal macrophages on chicken RBC. 小鼠ip酸吗啡0.3mg/kg×7d,0.6mg/kg×7d,能明显增加胸腺和脾脏的重量,能明显提高小鼠腹腔Mφ吞噬鸡红细胞的吞噬率和吞噬指数。
Morphine hydrochloride ( slow release tablet) was rectally administrated to the 43 females to treat cancer pain followed by the judgment of pain relief. 使用盐酸吗啡缓释片直肠给药对43例妇科肿瘤患者进行癌痛治疗,并判断疼痛症状缓解情况。
Methods 102 patients with moderate and severe pain were treated with morphine hydrochloride sustained-release tablets whose beginning usage was 30 mg/ 12 h, and the dosage was adjusted individually according to the analgesic effect. 方法对102例中、重度癌痛患者进行治疗,盐酸吗啡缓释片开始剂量为30mg,每12h服药1次,在用药的过程中根据疼痛缓解程度来调整剂量。
Morphine Hydrochloride Sustained-release Tablets for Treating Cancer Pain in 102 Cases 盐酸吗啡缓释片治疗晚期癌症疼痛102例
AIM: To investigate the effect of rectal administration of morphine hydrochloride ( slow release tablet) in significantly relieving cancer pain of patients with gynecologic tumors, and the impact of pain relief on the ability of activities and quality of life ( QOL) in patients. 目的:探讨使用盐酸吗啡缓释片直肠给药方式对妇科肿瘤患者癌痛的有效缓解以及对患者的活动能力和生活质量的影响。
Considered gastrointestinal tract side effects and the rescue analgesic dose, Oxycodone hydrochloride controlled-release tablets surpass the Morphine sulfate controlled-release tablets. Oxycodone hydrochloride controlled-release tablets may be a potential regimen for visceral cancer pain. 盐酸羟考酮控释片在解救药用量及常见副作用方面优于硫酸吗啡控释片,可作为癌性内脏痛治疗的优选药物。
The passage between the two boxes was blocked by the closure. Morphine hydrochloride and saline of the same volume were injected into the abdominal cavity of the two groups with morphine twice a day in the continuous six days. 隔板封闭两盒间通道,给吗啡两组大鼠连续6天每只上下午各腹腔注射一次,分别注射等体积盐酸吗啡和生理盐水。